Welcome to Coaginfo.com, The Coagulation Information Source, an Internet site designed for physicians and other health care personnel who want information about topics related to the pathophysiology, pharmacology, and clinical aspects of hemostasis, including therapeutic, pharmacologic, and monitoring approaches to managing coagulation disorders.

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Clinical applications of hemostatic agents are rapidly growing in clinical medicine. Because of the pivotal role of thrombosis in cardiovascular medicine, neurology, critical care, surgery, perioperative medicine, and oncology, therapeutic approaches to preventing both arterial and venous thrombosis are a cornerstone of therapy in this millennium. Newer heparins (eg, low molecular weight heparin), novel antithrombotic agents (eg, recombinant hirudin), the glycoprotein IIb/IIIa receptor antagonists, and clopidogrel (Plavix) have assumed a pivotal role in cardiology and clinical medicine. Many of these agents also pose a challenge to the physicians, and other health care personnel involved in their management due to the paradox between the need to prevent thrombosis in these patients and the need for therapeutic hemostasis at surgical sites or other sites of vascular injury. Biological agents (eg, antithrombin III and activated protein C) are also being evaluated in clinical trials and offer novel therapeutic applications of physiologic proteins. This site will explore important issues in managing these patients and understanding their applications. This site is sponsored by DocMD.com, an Internet site dedicated to bringing useful information to physicians and other healthcare personnel. Be sure to visit DocMD.com to keep up on what is new and interesting in healthcare, and for other helpful information. Please contact us at Info@DocMD.com if you have additional suggestions or comments.